[Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2].

Abstract : To evaluate whether fine air particles could be involved in the occurrence of atopy and allergic diseases, we performed a cross-sectional epidemiological survey involving primary schoolchildren living in six French towns with contrasted air pollution levels. Air pollution was measured during a week in the school yards and by standard air monitoring networks. Children get an examination in school looking for atopic dermatitis and bronchial hyperresponsiveness assessed by a standardized run test. Besides, parents or guardians provided past medical history and environmental data, especially on passive smoking. Overall, 5,338 children, aged 10.4 (+/-0.7) years, coming from 108 different schools and 401 different classes were included in the survey. Taking into account potential confounders, high exposure to proximity PM(2.5) was linked to a higher point prevalence of atopic dermatitis and hyperresponsiveness, to a higher cumulative prevalence of allergic asthma and a higher sensitization rate to common indoor allergens. Thus, these data suggest that chronic exposure to urban fine particles could be a risk factor for atopy, hyperresponsiveness and asthma.
docType_s : Journal articles
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Contributor : Annesi-Maesano Isabella <>
Submitted on : Tuesday, May 24, 2011 - 5:00:45 PM
Last modification on : Tuesday, May 24, 2011 - 5:00:45 PM

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I. Annesi-Maesano, D. Caillaud, F. Lavaud, D. Moreau, Y. Le Moullec, et al.. [Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2].. Archives de Pédiatrie, Elsevier, 2009, 16 (3), pp.299-305. <10.1016/j.arcped.2008.12.004>. <hal-00595449>

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