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Article Dans Une Revue Physical Review Letters Année : 2015

Homeostatic Fluctuations of a Tissue Surface

Thomas Risler

Résumé

We study the surface fluctuations of a tissue with a dynamics dictated by cell-rearrangement, cell-division, and cell-death processes. Surface fluctuations are calculated in the homeostatic state, where cell division and cell death equilibrate on average. The obtained fluctuation spectrum can be mapped onto several other spectra such as those characterizing incompressible fluids, compressible Maxwell elastomers, or permeable membranes in appropriate asymptotic regimes. Since cell division and cell death are out-of-equilibrium processes, detailed balance is broken, but a generalized fluctuation-response relation is satisfied in terms of appropriate observables. Our work is a first step toward the description of the out-of-equilibrium fluctuations of the surface of a thick epithelium and its dynamical response to external perturbations.
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Dates et versions

hal-01235789 , version 1 (30-11-2015)
hal-01235789 , version 2 (19-12-2015)

Identifiants

Citer

Thomas Risler, Aurélien Peilloux, Jacques Prost. Homeostatic Fluctuations of a Tissue Surface. Physical Review Letters, 2015, 115, pp.258104. ⟨10.1103/PhysRevLett.115.258104⟩. ⟨hal-01235789v2⟩
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