Practical modifications of the continual reassessment method for phase i cancer clinical trials, Journal of Biopharmaceutical Statistics, vol.31, issue.2, pp.147-64, 1994. ,
DOI : 10.1111/j.1472-8206.1990.tb00079.x
A comparison of two phase I trial designs, Stat Med, vol.13, pp.1799-806, 1994. ,
Experimental designs for phase I and phase I/II dose-finding studies, Br. J. Cancer, vol.94, issue.5, pp.609-613, 2006. ,
Perspectives on the development of a molecularly targeted agent, Cancer Cell, vol.1, issue.1, pp.31-36, 2002. ,
DOI : 10.1016/S1535-6108(02)00025-9
Antiangiogenic Therapy: More Promise and, Yet Again, More Questions, Journal of Clinical Oncology, vol.21, issue.21, pp.3897-3899, 2003. ,
DOI : 10.1200/JCO.2003.07.977
Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, in Patients With Advanced Colorectal Cancer and Liver Metastases: Results From Two Phase I Studies, Journal of Clinical Oncology, vol.21, issue.21, pp.3955-3964, 2003. ,
DOI : 10.1200/JCO.2003.08.092
A Bayesian dose-finding design for drug combination clinical trials based on the logistic model, Pharmaceutical Statistics, vol.58, issue.1, pp.247-257, 2014. ,
DOI : 10.1002/pst.1621
URL : https://hal.archives-ouvertes.fr/hal-01298657
A Bayesian dose finding design for clinical trials combining a cytotoxic agent with a molecularly targeted agent, Journal of the Royal Statistical Society: Series C (Applied Statistics), vol.10, issue.1, pp.215-229, 2015. ,
DOI : 10.1111/rssc.12072
URL : https://hal.archives-ouvertes.fr/hal-01298649
pocrm: An R-package for Phase I trials of combinations of agents, Computer Methods and Programs in Biomedicine, vol.112, issue.1, pp.211-218, 2013. ,
DOI : 10.1016/j.cmpb.2013.05.020
A product of independent beta probabilities dose escalation design for dual-agent phase I trials, Statistics in Medicine, vol.25, issue.12, pp.1261-1276, 2015. ,
DOI : 10.1002/sim.6434
Designs of drugcombination phase I trials in oncology: a systematic review of the literature, Ann. Oncol, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01298650
R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, 2014. ,