W. Robberecht and T. Philips, The changing scene of amyotrophic lateral sclerosis, Nature Reviews Neuroscience, vol.2, issue.4, pp.248-264, 2013.
DOI : 10.1038/nrn3430

B. Swinnen and W. Robberecht, The phenotypic variability of amyotrophic lateral sclerosis, Nature Reviews Neurology, vol.20, issue.11, pp.661-670, 2014.
DOI : 10.1007/s00401-010-0782-y

S. Paganoni, E. Macklin, A. Lee, A. Murphy, J. Chang et al., Diagnostic timelines and delays in diagnosing amyotrophic lateral sclerosis (ALS), Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol.139, issue.3, pp.453-456, 2014.
DOI : 10.1016/0022-510X(94)90191-0

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433003

J. Labra, P. Menon, K. Byth, S. Morrison, and S. Vucic, Rate of disease progression: a prognostic biomarker in ALS, Journal of Neurology, Neurosurgery & Psychiatry, vol.77, issue.(Suppl 3), pp.628-632, 2016.
DOI : 10.1136/jnnp-2015-310998

P. Gordon, F. Salachas, L. Lacomblez, N. Leforestier, P. Pradat et al., Predicting Survival of Patients with Amyotrophic Lateral Sclerosis at Presentation: A 15-Year Experience, Neurodegenerative Diseases, vol.12, issue.2, pp.81-90, 2013.
DOI : 10.1159/000341316

A. Chiò, G. Logroscino, O. Hardiman, R. Swingler, D. Mitchell et al., Prognostic factors in ALS: A critical review, Amyotrophic Lateral Sclerosis, vol.330, issue.5-6, pp.310-232, 2009.
DOI : 10.1111/j.1600-0404.2004.00362.x

B. Foerster, R. Welsh, and E. Feldman, 25 years of neuroimaging in amyotrophic lateral sclerosis, Nature Reviews Neurology, vol.19, issue.9, pp.513-524, 2013.
DOI : 10.1038/nrneurol.2013.153

F. Agosta, M. Rocca, P. Valsasina, S. Sala, D. Caputo et al., A longitudinal diffusion tensor MRI study of the cervical cord and brain in amyotrophic lateral sclerosis patients, Journal of Neurology, Neurosurgery & Psychiatry, vol.80, issue.1, pp.53-55, 2009.
DOI : 10.1136/jnnp.2008.154252

E. Mendili, M. Chen, R. Tiret, B. Villard, N. Trunet et al., Fast and Accurate Semi-Automated Segmentation Method of Spinal Cord MR Images at 3T Applied to the Construction of a Cervical Spinal Cord Template, PLOS ONE, vol.6, issue.3, 2014.
DOI : 10.1371/journal.pone.0122224.s002

URL : https://hal.archives-ouvertes.fr/hal-01233420

J. Cohen-adad, M. Mendili, R. Morizot-koutlidis, S. Lehéricy, V. Meininger et al., Involvement of spinal sensory pathway in ALS and specificity of cord atrophy to lower motor neuron degeneration, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol.73, issue.1, pp.30-38, 2013.
DOI : 10.1212/WNL.57.9.1571

J. Cohen-adad, W. Zhao, K. B. Ratai, E. Triantafyllou, C. Lawson et al., 7-T MRI of the spinal cord can detect lateral corticospinal tract abnormality in amyotrophic lateral sclerosis, Muscle & Nerve, vol.73, issue.suppl
DOI : 10.1002/mus.23720

G. Nair, J. Carew, S. Usher, D. Lu, X. Hu et al., Diffusion tensor imaging reveals regional differences in the cervical spinal cord in amyotrophic lateral sclerosis, NeuroImage, vol.53, issue.2, pp.576-583, 2010.
DOI : 10.1016/j.neuroimage.2010.06.060

P. Valsasina, F. Agosta, B. Benedetti, D. Caputo, M. Perini et al., Diffusion anisotropy of the cervical cord is strictly associated with disability in amyotrophic lateral sclerosis, Journal of Neurology, Neurosurgery & Psychiatry, vol.78, issue.5, pp.480-484, 2007.
DOI : 10.1136/jnnp.2006.100032

L. Branco, M. De-albuquerque, D. Andrade, H. Bergo, F. Nucci et al., Spinal cord atrophy correlates with disease duration and severity in amyotrophic lateral sclerosis, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol.14, issue.1-2, pp.93-97, 2014.
DOI : 10.1212/WNL.47.2.535

E. Mendili, M. Cohen-adad, J. Pellegrini-issac, M. Rossignol, S. Morizot-koutidis et al., Multi-Parametric Spinal Cord MRI as Potential Progression Marker in Amyotrophic Lateral Sclerosis, PLoS ONE, vol.130, issue.4, 2014.
DOI : 10.1371/journal.pone.0095516.t004

URL : https://hal.archives-ouvertes.fr/hal-01358128

J. Cedarbaum, N. Stambler, E. Malta, C. Fuller, D. Hilt et al., The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function, Journal of the Neurological Sciences, vol.169, issue.1-2, pp.13-21, 1994.
DOI : 10.1016/S0022-510X(99)00210-5

G. Lakes and A. Group, A comparison of muscle strength testing techniques in amyotrophic lateral sclerosis, Neurology, vol.61, pp.1503-1507, 2003.

E. Mendili, M. Chen, R. Tiret, B. Pélégrini-issac, M. Cohen-adad et al., Validation of a semiautomated spinal cord segmentation method, Journal of Magnetic Resonance Imaging, vol.266, issue.Pt 3, pp.454-463
DOI : 10.1002/jmri.24571

E. Mendili, M. Lenglet, T. Stojkovic, T. Behin, A. Guimares-costa et al., Cervical spinal cord atrophy profile in adult SMN1-linked SMA, Plos One, vol.11, issue.4, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01304374

J. Cohen-adad, E. Mendili, M. Lehéricy, S. Pradat, P. Blancho et al., Demyelination and degeneration in the injured human spinal cord detected with diffusion and magnetization transfer MRI, NeuroImage, vol.55, issue.3, pp.1024-1033, 2011.
DOI : 10.1016/j.neuroimage.2010.11.089

T. Lawyer and M. Netsky, AMYOTROPHIC LATERAL SCLEROSIS, A.M.A. Archives of Neurology & Psychiatry, vol.69, issue.2, pp.171-92, 1953.
DOI : 10.1001/archneurpsyc.1953.02320260029002

F. Cruz-sanchez, A. Moral, E. Tolosa, J. De-belleroche, and M. Rossi, Evaluation of neuronal loss, astrocytosis and abnormalities of cytoskeletal components of large motor neurons in the human anterior horn in aging, Journal of Neural Transmission, vol.105, issue.6-7, pp.689-701, 1998.
DOI : 10.1007/s007020050088

E. Verstraete, D. Polders, R. Mandl, M. Van-der-heuvel, J. Veldink et al., Multimodal tract-based analysis in ALS patients at 7T: A specific white matter profile?, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol.240, issue.1, pp.84-92, 2014.
DOI : 10.3171/jns.1999.90.1.0109

H. Blasco, P. Vourc-'h, P. Pradat, P. Gordon, C. Andres et al., Further development of biomarkers in amyotrophic lateral sclerosis, Expert Review of Molecular Diagnostics, vol.2014, issue.9, pp.853-68, 2016.
DOI : 10.3109/17482968.2010.513052

R. Menke, F. Agosta, J. Grosskreutz, M. Filippi, and M. Turner, Neuroimaging Endpoints in Amyotrophic Lateral Sclerosis, Neurotherapeutics, vol.137, issue.Suppl. 2, pp.10-1007, 2016.
DOI : 10.1007/s13311-016-0484-9

H. Van-der-burgh, R. Schmidt, H. Westeneng, M. De-reus, L. Van-den-berg et al., Deep learning predictions of survival based on MRI in amyotrophic lateral sclerosis, NeuroImage: Clinical, vol.13, pp.361-369, 2016.
DOI : 10.1016/j.nicl.2016.10.008

G. Grolez, C. Moreau, V. Danel-brunaud, C. Delmaire, R. Lopes et al., The value of magnetic resonance imaging as a biomarker for amyotrophic lateral sclerosis: a systematic review, BMC Neurology, vol.87, issue.6, pp.155-165, 2016.
DOI : 10.1186/s12883-016-0672-6

URL : https://hal.archives-ouvertes.fr/hal-01357813