M. A. Burchill, J. Yang, C. Vogtenhuber, B. R. Blazar, and M. A. Farrar, IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3, 2007.

A. C. Chan, C. , and P. J. , Therapeutic antibodies for autoimmunity and inflammation, Nature Reviews Immunology, vol.10, issue.5, pp.301-316, 2010.
DOI : 10.4049/jimmunol.169.9.5171

Q. Chen, Y. C. Kim, A. Laurence, G. A. Punkosdy, and E. M. Shevach, IL-2 Controls the Stability of Foxp3 Expression in TGF-??-Induced Foxp3+ T Cells In Vivo, The Journal of Immunology, vol.186, issue.11, pp.6329-6337, 2011.
DOI : 10.4049/jimmunol.1100061

W. Chen, W. Jin, N. Hardegen, K. J. Lei, L. Li et al., Conversion of peripheral CD4+CD25? naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3, 2003.

X. Chen, M. Baumel, D. N. Mannel, O. M. Howard, and J. J. Oppenheim, Interaction of TNF with TNF Receptor Type 2 Promotes Expansion and Function of Mouse CD4+CD25+ T Regulatory Cells, The Journal of Immunology, vol.179, issue.1, pp.154-161, 2007.
DOI : 10.4049/jimmunol.179.1.154

X. Chen and J. J. Oppenheim, TNF-α: An Activator of CD4+FoxP3+TNFR2+ Regulatory T Cells, Curr. Dir. Autoimmun, vol.11, pp.119-134, 2010.
DOI : 10.1159/000289201

J. L. Bgt038-coombes, K. R. Siddiqui, C. V. Arancibia-carcamo, J. Hall, C. M. Sun et al., A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism, Carcinogenesis J. Exp. Med, vol.34, issue.204, pp.1296-1303, 2007.

M. A. Curotto-de-lafaille, J. J. Lafaille, T. S. Immuni-davidson, R. J. Dipaolo, J. Andersson et al., Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells, Immunity J. Immunol, vol.30, issue.178, pp.626-635, 2007.

S. Floess, J. Freyer, C. Siewert, U. Baron, S. Olek et al., Epigenetic Control of the foxp3 Locus in Regulatory T Cells, PLoS Biology, vol.31, issue.2, 2007.
DOI : 10.1371/journal.pbio.0050038.st001

J. D. Fontenot, J. L. Dooley, A. G. Farr, and A. Y. Rudensky, Developmental regulation of Foxp3 expression during ontogeny, The Journal of Experimental Medicine, vol.105, issue.7, pp.901-906, 2005.
DOI : 10.3109/08916939908993801

J. D. Fontenot, J. P. Rasmussen, M. A. Gavin, A. Y. Rudensky, J. D. Fontenot et al., A function for interleukin 2 in Foxp3-expressing regulatory T cells doi:10 Foxp3 programs the development and function of CD4+CD25+ regulatory T cells Interleukin 2 signaling is required for CD4(+) regulatory T cell function, Nat. Immunol. Nat. Immunol. J. Exp. Med, vol.6, issue.196, pp.1142-1151, 1038.

M. A. Gavin, J. P. Rasmussen, J. D. Fontenot, V. Vasta, V. C. Manganiello et al., Foxp3- dependent programme of regulatory T-cell differentiation Continuous activation of the CD122/STAT- 5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus, Nature PLoS ONE, vol.445, issue.6, pp.771-775, 2007.

L. Gorelik and R. A. Flavell, Abrogation of TGF?? Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease, Immunity, vol.12, issue.2, pp.171-181, 2000.
DOI : 10.1016/S1074-7613(00)80170-3

A. Goubier, B. Dubois, H. Gheit, G. Joubert, F. Villard-truc et al., Plasmacytoid Dendritic Cells Mediate Oral Tolerance, Immunity, vol.29, issue.3, pp.464-475, 2008.
DOI : 10.1016/j.immuni.2008.06.017
URL : http://doi.org/10.1016/j.immuni.2008.06.017

J. R. Grainger, K. A. Smith, J. P. Hewitson, H. J. Mcsorley, Y. Harcus et al., Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-?? pathway, The Journal of Experimental Medicine, vol.207, issue.11, pp.2331-2341, 2010.
DOI : 10.1038/nri1806
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964568/pdf

M. Grell, F. M. Becke, H. Wajant, D. N. Mannel, P. Scheurich et al., TNF receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1 IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells, Eur. J. Immunol. J. Exp. Med, vol.2828, issue.207, pp.257-263, 1998.

P. Hamano, R. Huang, J. Yoshimura, T. Oppenheim, J. J. et al., TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40, European Journal of Immunology, vol.11, issue.7, pp.4558-4568, 2011.
DOI : 10.1159/000289201
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783213

D. Haribhai, J. B. Williams, S. Jia, D. Nickerson, E. G. Schmitt et al., A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity, Immunity, vol.35, issue.1, pp.109-122, 2011.
DOI : 10.1016/j.immuni.2011.03.029

S. Haxhinasto, D. Mathis, and C. Benoist, cells, The Journal of Experimental Medicine, vol.70, issue.3, pp.565-574, 2008.
DOI : 10.1073/pnas.0409832102

J. A. Hill, M. Feuerer, K. Tash, S. Haxhinasto, J. Perez et al., Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature, Immunity, vol.27, issue.5, pp.786-800, 2007.
DOI : 10.1016/j.immuni.2007.09.010

S. Hori, T. Nomura, and S. Sakaguchi, Control of Regulatory T Cell Development by the Transcription Factor Foxp3, Science, vol.299, issue.5609, pp.1057-1061, 2003.
DOI : 10.1126/science.1079490

W. J. Housley, C. O. Adams, F. C. Nichols, L. Puddington, E. G. Lingenheld et al., Natural but Not Inducible Regulatory T Cells Require TNF-?? Signaling for In Vivo Function, The Journal of Immunology, vol.186, issue.12, pp.6779-6787, 2011.
DOI : 10.4049/jimmunol.1003868

C. S. Hsieh, Y. Zheng, Y. Liang, J. D. Fontenot, A. Y. Rudensky et al., An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires, Nature Immunology, vol.164, issue.4, pp.401-410, 1318.
DOI : 10.4049/jimmunol.164.11.5782

R. Jabeen and M. H. Kaplan, The symphony of the ninth: the development and function of Th9 cells, Current Opinion in Immunology, vol.24, issue.3, 2012.
DOI : 10.1016/j.coi.2012.02.001

C. O. Jacob and H. O. Mcdevitt, Tumour necrosis factor-?? in murine autoimmune 'lupus' nephritis, Nature, vol.331, issue.6154, pp.356-358, 1988.
DOI : 10.1038/331356a0

M. S. Jordan, A. Boesteanu, A. J. Reed, A. L. Petrone, A. E. Holenbeck et al., Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide, Nature Immunology, vol.180, issue.4, pp.301-3061086302, 1038.
DOI : 10.1038/86302

S. Z. Josefowicz, R. E. Niec, H. Y. Kim, P. Treuting, T. Chinen et al., Extrathymically generated regulatory T cells control mucosal TH2 inflammation, Nature, vol.11, issue.7385, pp.395-399, 2012.
DOI : 10.1186/gb-2010-11-10-r106
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485072

D. H. Kaplan, M. O. Li, M. C. Jenison, W. D. Shlomchik, R. A. Flavell et al., Autocrine/paracrine TGF??1 is required for the development of epidermal Langerhans cells, The Journal of Experimental Medicine, vol.157, issue.11, pp.2545-2552, 2007.
DOI : 10.1093/intimm/5.10.1329

J. Karman, J. L. Jiang, N. Gumlaw, H. Zhao, J. Campos-rivera et al., Regulatory T Cells, Journal of Biological Chemistry, vol.182, issue.14, 2012.
DOI : 10.1093/intimm/dxg017

F. S. Kleijwegt, S. Laban, G. Duinkerken, A. M. Joosten, A. Zaldumbide et al., Critical Role for TNF in the Induction of Human Antigen-Specific Regulatory T Cells by Tolerogenic Dendritic Cells, The Journal of Immunology, vol.185, issue.3, pp.1412-1418, 2010.
DOI : 10.4049/jimmunol.1000560

B. Knoechel, J. Lohr, E. Kahn, J. A. Bluestone, and A. K. Abbas, Sequential development of interleukin 2???dependent effector and regulatory T cells in response to endogenous systemic antigen, The Journal of Experimental Medicine, vol.14, issue.10, 2005.
DOI : 10.1038/ni909

N. Komatsu, M. E. Mariotti-ferrandiz, Y. Wang, B. Malissen, H. Waldmann et al., T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity, Proc. Natl, 2009.
DOI : 10.1073/pnas.0702004104
URL : https://hal.archives-ouvertes.fr/hal-00407810

K. Kretschmer, I. Apostolou, D. Hawiger, K. Khazaie, M. C. Nussenzweig et al., Inducing and expanding regulatory T cell populations by foreign antigen, Nature Immunology, vol.5, issue.12, pp.2055-2066, 1038.
DOI : 10.4049/jimmunol.173.11.6526

A. Laurence, C. M. Tato, T. S. Davidson, Y. Kanno, Z. Chen et al., Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation, Immunity, vol.26, issue.3, pp.371-381, 2007.
DOI : 10.1016/j.immuni.2007.02.009
URL : http://doi.org/10.1016/j.immuni.2007.02.009

P. Leveen, J. Larsson, M. Ehinger, C. M. Cilio, M. Sundler et al., Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable, Blood, vol.100, issue.2, pp.560-568, 2002.
DOI : 10.1182/blood.V100.2.560

M. O. Li, S. Sanjabi, and R. A. Flavell, Transforming Growth Factor-?? Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent Mechanisms, Immunity, vol.25, issue.3, pp.455-471, 2006.
DOI : 10.1016/j.immuni.2006.07.011

W. Lin, D. Haribhai, L. M. Relland, N. Truong, M. R. Carlson et al., Regulatory T cell development in the absence of functional Foxp3, Nature Immunology, vol.174, issue.4, pp.359-368, 2007.
DOI : 10.1186/gb-2004-5-10-r80

A. Liston, A. Enders, and O. M. Siggs, Unravelling the association of partial T-cell immunodeficiency and immune dysregulation, Nature Reviews Immunology, vol.9, issue.7, pp.545-558, 2008.
DOI : 10.1007/s004310100816

A. Liston, O. M. Siggs, and C. C. Goodnow, Tracing the action of IL-2 in tolerance to islet-specific antigen, Immunology and Cell Biology, vol.175, issue.4, pp.338-342, 2007.
DOI : 10.1016/S1074-7613(00)80478-1

V. C. Liu, L. Y. Wong, T. Jang, A. H. Shah, I. Park et al., Tumor Evasion of the Immune System by Converting CD4+CD25- T Cells into CD4+CD25+ T Regulatory Cells: Role of Tumor-Derived TGF-??, The Journal of Immunology, vol.178, issue.5, pp.2883-2892, 2007.
DOI : 10.4049/jimmunol.178.5.2883

M. S. Maddur, P. Miossec, S. V. Kaveri, and J. Bayry, Th17 Cells, The American Journal of Pathology, vol.181, issue.1, pp.8-18, 2012.
DOI : 10.1016/j.ajpath.2012.03.044
URL : https://hal.archives-ouvertes.fr/hal-01102873

J. C. Marie, D. Liggitt, A. Y. Rudensky, and J. , Cellular mech Gliemann Urokinase receptor. An activation antigen in human T lymphocytes, J. Immunol, vol.152, pp.505-516, 1994.

J. C. Ochando, C. Homma, Y. Yang, A. Hidalgo, A. Garin et al., Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts, Nature Immunology, vol.16, issue.6, pp.652-662, 1994.
DOI : 10.4049/jimmunol.173.7.4433

N. Ohkura, M. Hamaguchi, H. Morikawa, K. Sugimura, A. Tanaka et al., T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development, Immunity, vol.37, issue.5, pp.785-799, 2012.
DOI : 10.1016/j.immuni.2012.09.010
URL : http://doi.org/10.1016/j.immuni.2012.09.010

N. Ohkura, Y. Kitagawa, and S. Sakaguchi, Development and Maintenance of Regulatory T??cells, Immunity, vol.38, issue.3, pp.414-423, 2013.
DOI : 10.1016/j.immuni.2013.03.002

G. Oldenhove, N. Bouladoux, E. A. Wohlfert, J. A. Hall, D. Chou et al., Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection, Immunity, vol.31, issue.5, pp.772-786, 2009.
DOI : 10.1016/j.immuni.2009.10.001

L. Passerini, S. E. Allan, M. Battaglia, D. Nunzio, S. Alstad et al., STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25? effector T cells Biologicsinduced autoimmune diseases, and BIOGEAS study group, pp.421-431, 1097.

J. K. Polansky, K. Kretschmer, J. Freyer, S. Floess, A. Garbe et al., DNA methylation controls Foxp3 gene expression, European Journal of Immunology, vol.175, issue.6, pp.1654-1663, 2008.
DOI : 10.4049/jimmunol.175.3.1694

G. J. Prud-'homme, Pathobiology of transforming growth factor ?? in cancer, fibrosis and immunologic disease, and therapeutic considerations, Laboratory Investigation, vol.34, issue.11, pp.1077-1091, 2007.
DOI : 10.1111/j.0105-2896.2006.00410.x

H. Rauert, A. Wicovsky, N. Muller, D. Siegmund, V. Spindler et al., Membrane Tumor Necrosis Factor (TNF) Induces p100 Processing via TNF Receptor-2 (TNFR2), Journal of Biological Chemistry, vol.172, issue.10, 2010.
DOI : 10.4049/jimmunol.172.2.752
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844188

Y. P. Rubtsov, R. E. Niec, S. Josefowicz, L. Li, J. Darce et al., Stability of the Regulatory T Cell Lineage in Vivo, Science, vol.463, issue.7282, pp.1667-1671, 2010.
DOI : 10.1038/nature08750

N. H. Ruddle, C. M. Bergman, K. M. Mcgrath, E. G. Lingenheld, M. L. Grunnet et al., An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis, Journal of Experimental Medicine, vol.172, issue.4, 1990.
DOI : 10.1084/jem.172.4.1193

D. Saadoun, M. Rosenzwajg, F. Joly, A. Six, F. Carrat et al., Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis, New England Journal of Medicine, vol.365, issue.22, pp.2067-2077, 1995.
DOI : 10.1056/NEJMoa1105143

B. Sadlack, H. Merz, H. Schorle, A. Schimpl, A. C. Feller et al., Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25) Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases, Cell J. Immunol, vol.759380067, issue.155, pp.253-261, 1993.

E. Sgouroudis, A. Albanese, and C. A. Piccirillo, Impact of Protective IL-2 Allelic Variants on CD4+Foxp3+ Regulatory T Cell Function In Situ and Resistance to Autoimmune Diabetes in NOD Mice, The Journal of Immunology, vol.181, issue.9, pp.6283-6292, 2008.
DOI : 10.4049/jimmunol.181.9.6283

E. Sgouroudis, M. Kornete, and C. A. Piccirillo, regulatory T-cell expansion in autoimmune-resistant NOD congenic mice, Autoimmunity, vol.181, issue.5, pp.406-414, 2011.
DOI : 10.4049/jimmunol.181.11.7449

H. J. Shin, J. Baker, D. B. Leveson-gower, A. T. Smith, E. I. Sega et al., Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells, Blood, vol.118, issue.8, pp.2342-2350, 2011.
DOI : 10.1182/blood-2010-10-313684

M. M. Shull, I. Ormsby, A. B. Kier, S. Pawlowski, R. J. Diebold et al., Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease Functional and molecular characteristics of T-cell growth factor IL-2Rbeta links IL-2R signaling with Foxp3 expression, Nature Mol. Immunol. Eur. J. Immunol, vol.359, issue.37, pp.693-699, 1980.

N. Sugimoto, T. Oida, K. Hirota, K. Nakamura, T. Nomura et al., Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis, International Immunology, vol.18, issue.8, 2006.
DOI : 10.1093/intimm/dxl060
URL : http://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/135673/1/yigak03053.pdf

C. M. Sun, J. A. Hall, R. B. Blank, N. Bouladoux, M. Oukka et al., Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid, The Journal of Experimental Medicine, vol.398, issue.8, pp.1197-1209, 2007.
DOI : 10.1084/jem.188.2.287

S. C. Sun, Non-canonical NF-??B signaling pathway, Cell Research, vol.175, issue.1, pp.71-85, 2011.
DOI : 10.1073/pnas.0907200106
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193406

H. Suzuki, T. M. Kundig, C. Furlonger, A. Wakeham, E. Timms et al., Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta, Science, vol.268, issue.5216, pp.1472-1476, 1995.
DOI : 10.1126/science.7770771

Q. Tang, J. Y. Adams, C. Penaranda, K. Melli, E. Piaggio et al., Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction, Immunity, vol.28, issue.5, pp.687-697, 2008.
DOI : 10.1016/j.immuni.2008.03.016

J. A. Todd, N. M. Walker, J. D. Cooper, D. J. Smyth, K. Downes et al., Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes, Nature Genetics, vol.175, issue.7, pp.857-864, 2007.
DOI : 10.1101/gr.3185605

Y. Tone, K. Furuuchi, Y. Kojima, M. L. Tykocinski, M. I. Greene et al., Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer, Nature Immunology, vol.85, issue.2, pp.194-202, 2006.
DOI : 10.4049/jimmunol.178.7.4022

G. J. Van-mierlo, H. U. Scherer, M. Hameetman, M. E. Morgan, R. Flierman et al., Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators, The Journal of Immunology, vol.180, issue.5, pp.2747-2751, 2008.
DOI : 10.4049/jimmunol.180.5.2747

A. Vella, J. D. Cooper, C. E. Lowe, N. Walker, S. Nutland et al., Localization of a Type 1 Diabetes Locus in the IL2RA/CD25 Region by Use of Tag Single-Nucleotide Polymorphisms, The American Journal of Human Genetics, vol.76, issue.5, pp.773-779, 2005.
DOI : 10.1086/429843

D. A. Vignali, L. W. Collison, C. J. Workman, M. R. Walker, D. J. Kasprowicz et al., How regulatory T cells work, Nature Reviews Immunology, vol.178, issue.7, pp.523-532, 2003.
DOI : 10.4049/jimmunol.178.5.2883

K. E. Webster, S. Walters, R. E. Kohler, T. Mrkvan, O. Boyman et al., In vivo expansion of T reg cells with IL-2???mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression, The Journal of Experimental Medicine, vol.155, issue.4, pp.751-760, 2009.
DOI : 10.1126/science.180605

D. O. Willenborg, S. A. Fordham, W. B. Cowden, R. , I. A. Willerford et al., Cytokines and Murine Autoimmune Encephalomyelitis: Inhibition or Enhancement of Disease with Antibodies to Select Cytokines, or by Delivery of Exogenous Cytokines Using a Recombinant Vaccinia Virus System, Scandinavian Journal of Immunology, vol.124, issue.1, pp.31-41, 1995.
DOI : 10.1016/0167-5699(94)90075-2

M. S. Wilson, J. T. Pesce, T. R. Ramalingam, R. W. Thompson, A. Cheever et al., Suppression of Murine Allergic Airway Disease by IL-2:Anti-IL-2 Monoclonal Antibody-Induced Regulatory T Cells, The Journal of Immunology, vol.181, issue.10, pp.6942-6954, 2008.
DOI : 10.4049/jimmunol.181.10.6942

E. A. Wohlfert, J. R. Grainger, N. Bouladoux, J. E. Konkel, G. Oldenhove et al., GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice, Journal of Clinical Investigation, vol.121, issue.11, pp.4503-451510, 1172.
DOI : 10.1172/JCI57456DS1
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204837

Y. Wu, M. Borde, V. Heissmeyer, M. Feuerer, A. D. Lapan et al., FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT, Cell, vol.126, issue.2, pp.375-387, 2006.
DOI : 10.1016/j.cell.2006.05.042
URL : http://doi.org/10.1016/j.cell.2006.05.042

L. Xu, A. Kitani, and W. Strober, Molecular mechanisms regulating TGF-??-induced Foxp3 expression, Mucosal Immunology, vol.181, issue.3, pp.230-238, 2010.
DOI : 10.1182/blood-2007-06-096438
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673708

J. Yamanouchi, D. Rainbow, P. Serra, S. Howlett, K. Hunter et al., Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity, Nature Genetics, vol.33, issue.3, pp.329-337, 1182.
DOI : 10.1074/jbc.M501459200
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886969

X. D. Yang, R. Tisch, S. M. Singer, Z. A. Cao, R. S. Liblau et al., Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process, Journal of Experimental Medicine, vol.180, issue.3, pp.995-1004, 1994.
DOI : 10.1084/jem.180.3.995

Z. Yao, Y. Kanno, M. Kerenyi, G. Stephens, L. Durant et al., Nonredundant roles for Stat5a/b in directly regulating Foxp3, Blood, vol.109, issue.10, pp.4368-4375, 2007.
DOI : 10.1182/blood-2006-11-055756
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885496

A. Zanin-zhorov, Y. Ding, S. Kumari, M. Attur, K. L. Hippen et al., Protein Kinase C-?? Mediates Negative Feedback on Regulatory T Cell Function, Science, vol.30, issue.5, pp.372-376, 2010.
DOI : 10.1016/j.immuni.2009.04.006
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905626

Y. Zheng, S. Josefowicz, A. Chaudhry, X. P. Peng, K. Forbush et al., Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate, Nature, vol.204, issue.7282, pp.808-81210, 1038.
DOI : 10.4049/jimmunol.170.7.3724

X. Zhou, S. L. Bailey-bucktrout, L. T. Jeker, C. Penaranda, M. Martinez-llordella et al., Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo, Nature Immunology, vol.34, issue.9, pp.1000-1007, 2009.
DOI : 10.4049/jimmunol.182.1.259

E. Zorn, E. A. Nelson, M. Mohseni, F. Porcheray, H. Kim et al., IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo, Blood, vol.108, issue.5, pp.1571-1579, 2006.
DOI : 10.1182/blood-2006-02-004747