Y. Murakami, H. Matsumoto, and M. Roh, Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration, Proceedings of the National Academy of Sciences, vol.309, issue.2, pp.14598-14603, 2012.
DOI : 10.1124/jpet.103.062034

Z. Jin, S. Okamoto, M. Mandai, and M. Takahashi, Induced pluripotent stem cells for retinal degenerative diseases: a new perspective on the challenges, Journal of Genetics, vol.324, issue.4, pp.417-424, 2009.
DOI : 10.1016/B978-0-323-02598-0.50023-9

K. Takahashi, K. Tanabe, and M. Ohnuki, Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors, Cell, vol.131, issue.5, pp.861-872, 2007.
DOI : 10.1016/j.cell.2007.11.019

J. Yu, K. Hu, and K. Smuga-otto, Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences, Science, vol.26, issue.7, pp.797-801, 2009.
DOI : 10.1038/nbt1418

I. Verma and N. Somia, Gene Therapy: Promises, Problems and Prospects, Nature, vol.389, issue.6648, pp.239-242, 1997.
DOI : 10.1007/978-3-642-56947-0_13

T. Hollon, Researchers and regulators reflect on first gene therapy death., American Journal of Ophthalmology, vol.129, issue.5, p.701, 2000.
DOI : 10.1016/S0002-9394(00)00442-6

E. Check, Gene therapy put on hold as third child develops cancer, Nature, vol.433, issue.7026, p.561, 2005.
DOI : 10.1038/433561a

M. Cavazzana-calvo, A. Thrasher, and F. Mavilio, The future of gene therapy, Nature, vol.427, issue.6977, pp.779-781, 2004.
DOI : 10.1038/427779a

J. Yu, K. Hu, and K. Smuga-otto, Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences, Science, vol.26, issue.7, pp.797-801, 2009.
DOI : 10.1038/nbt1418

B. Chou, P. Mali, and X. Huang, Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures, Cell Research, vol.460, issue.3, pp.518-529, 2011.
DOI : 10.1038/nature08592

W. Li, K. Jiang, and S. Ding, Concise Review: A Chemical Approach to Control Cell Fate and Function, STEM CELLS, vol.6, issue.1, pp.61-68, 2012.
DOI : 10.4161/cc.6.24.5129

URL : http://onlinelibrary.wiley.com/doi/10.1002/stem.768/pdf

K. Narsinh, F. Jia, R. Robbins, M. Kay, M. Longaker et al., Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors, Nature Protocols, vol.2, issue.1, pp.78-88, 2011.
DOI : 10.1006/meth.2001.1262

D. Kim, C. Kim, and J. Moon, Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins, Cell Stem Cell, vol.4, issue.6, pp.472-476, 2009.
DOI : 10.1016/j.stem.2009.05.005

H. Zhou, S. Wu, and J. Joo, Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins, Cell Stem Cell, vol.4, issue.5, pp.381-384, 2009.
DOI : 10.1016/j.stem.2009.04.005

L. Warren, P. Manos, and T. Ahfeldt, Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA, Cell Stem Cell, vol.7, issue.5, pp.618-630, 2010.
DOI : 10.1016/j.stem.2010.08.012

K. Okita and S. Yamanaka, Induced pluripotent stem cells: opportunities and challenges, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.27, issue.11, pp.2198-2207, 1575.
DOI : 10.1038/nbt.1580

Y. Gheisari, M. Soleimani, K. Azadmanesh, and S. Zeinali, Multipotent mesenchymal stromal cells: optimization and comparison of five cationic polymer-based gene delivery methods, Cytotherapy, vol.10, issue.8, pp.815-823, 2008.
DOI : 10.1080/14653240802474307

M. Yalvac, M. Ramazanoglu, O. Gumru, F. Sahin, A. Palotas et al., Comparison and Optimisation of Transfection of Human Dental Follicle Cells, a Novel Source of Stem Cells, with Different Chemical Methods and Electro-poration, Neurochemical Research, vol.3, issue.286, pp.1272-1277, 2009.
DOI : 10.1172/JCI200316502

C. Srinivasan and D. Burgess, Optimization and characterization of anionic lipoplexes for gene delivery, Journal of Controlled Release, vol.136, issue.1, pp.62-70, 2009.
DOI : 10.1016/j.jconrel.2009.01.022

D. Lynn and R. Langer, Degradable Poly(??-amino esters):?? Synthesis, Characterization, and Self-Assembly with Plasmid DNA, Journal of the American Chemical Society, vol.122, issue.44, pp.10761-10768, 2000.
DOI : 10.1021/ja0015388

N. Bhise, R. Shmueli, J. Gonzalez, and J. Green, A Novel Assay for Quantifying the Number of Plasmids Encapsulated by Polymer Nanoparticles, Small, vol.19, issue.3, pp.367-373, 2012.
DOI : 10.1002/adma.200700371

J. Green, G. Zugates, and N. Tedford, Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus, Advanced Materials, vol.92, issue.19, pp.2836-2842, 2007.
DOI : 10.1002/adma.200700371

N. Bhise, R. Gray, J. Sunshine, S. Htet, A. Ewald et al., The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures, Biomaterials, vol.31, issue.31, pp.318088-8096, 2010.
DOI : 10.1016/j.biomaterials.2010.07.023

J. Sunshine, M. Akanda, D. Li, K. Kozielski, and J. Green, Effects of Base Polymer Hydrophobicity and End-Group Modification on Polymeric Gene Delivery, Biomacromolecules, vol.12, issue.10, pp.3592-3600, 2011.
DOI : 10.1021/bm200807s

S. Tzeng, H. Guerrero-cazares, E. Martinez, J. Sunshine, A. Quinones-hinojosa et al., Non-viral gene delivery nanoparticles based on Poly(??-amino esters) for treatment of glioblastoma, Biomaterials, vol.32, issue.23, pp.5402-5410, 2011.
DOI : 10.1016/j.biomaterials.2011.04.016

J. Sunshine, N. Bhise, and J. Green, Degradable polymers for gene delivery, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp.2412-2415, 2009.
DOI : 10.1109/IEMBS.2009.5334767

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959118

J. Meyer, R. Shearer, and E. Capowski, Modeling early retinal development with human embryonic and induced pluripotent stem cells, Proceedings of the National Academy of Sciences, vol.49, issue.2, pp.16698-16703, 2009.
DOI : 10.1167/iovs.07-0777

J. Synnergren, T. Giesler, and S. Adak, Differentiating Human Embryonic Stem Cells Express a Unique Housekeeping Gene Signature, Stem Cells, vol.337, issue.2, pp.473-480, 2007.
DOI : 10.1038/labinvest.3700208

K. Hochedlinger and K. Plath, Epigenetic reprogramming and induced pluripotency, Development, vol.136, issue.4, pp.509-523, 2009.
DOI : 10.1242/dev.020867

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685952

S. Hung, M. Kang, and E. Kieff, Maintenance of Epstein-Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1, Proceedings of the National Academy of Sciences, vol.109, issue.5, pp.1865-1870, 2001.
DOI : 10.1083/jcb.109.5.1963

P. Mali, Z. Ye, B. Chou, Y. J. Cheng, and L. , An Improved Method for Generating and Identifying Human Induced Pluripotent Stem Cells, Methods Mol Biol, vol.636, pp.191-205, 2010.
DOI : 10.1007/978-1-60761-691-7_12

K. Hasegawa, T. Fujioka, Y. Nakamura, N. Nakatsuji, and H. Suemori, A Method for the Selection of Human Embryonic Stem Cell Sublines with High Replating Efficiency After Single-Cell Dissociation, Stem Cells, vol.23, issue.12, pp.2649-2660, 2006.
DOI : 10.1634/stemcells.2005-0657

J. Ji, S. Ng, and V. Sharma, Elevated Coding Mutation Rate During the Reprogramming of Human Somatic Cells into Induced Pluripotent Stem Cells, STEM CELLS, vol.291, issue.3, pp.435-440, 2012.
DOI : 10.1126/science.1056154

A. Stover and P. Schwartz, Adaptation of Human Pluripotent Stem Cells to Feeder-Free Conditions in Chemically Defined Medium with Enzymatic Single-Cell Passaging, Methods Mol Biol, vol.767, pp.137-146, 2011.
DOI : 10.1007/978-1-61779-201-4_10

M. Nakagawa, M. Koyanagi, and K. Tanabe, Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts, Nature Biotechnology, vol.93, issue.1, pp.101-106, 2008.
DOI : 10.1073/pnas.93.24.14041

V. Ramos-mejia, R. Montes, and C. Bueno, Residual Expression of the Reprogramming Factors Prevents Differentiation of iPSC Generated from Human Fibroblasts and Cord Blood CD34+ Progenitors, PLoS ONE, vol.40, issue.4, p.35824, 2012.
DOI : 10.1371/journal.pone.0035824.s002

C. Sommer, A. Sommer, and T. Longmire, Excision of Reprogramming Transgenes Improves the Differentiation Potential of iPS Cells Generated with a Single Excisable Vector, Stem Cells, vol.28, issue.1, pp.64-74, 2010.
DOI : 10.1002/stem.255

N. Montserrat, E. Garreta, and F. Gonzalez, Simple Generation of Human Induced Pluripotent Stem Cells Using Poly-??-amino Esters As the Non-viral Gene Delivery System, Journal of Biological Chemistry, vol.11, issue.14, pp.12417-12428, 2011.
DOI : 10.1016/j.stem.2008.06.019

A. Giorgetti, N. Montserrat, and T. Aasen, Generation of Induced Pluripotent Stem Cells from Human Cord Blood Using OCT4 and SOX2, Cell Stem Cell, vol.5, issue.4, pp.353-357, 2009.
DOI : 10.1016/j.stem.2009.09.008

T. Aasen, A. Raya, and M. Barrero, Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes, Nature Biotechnology, vol.99, issue.11, pp.1276-1284, 2008.
DOI : 10.1038/nbt.1503

S. Goldstein, Replicative senescence: the human fibroblast comes of age, Science, vol.249, issue.4973, pp.1129-1133, 1990.
DOI : 10.1126/science.2204114

I. Yoon, H. Kim, and Y. Kim, Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology, Experimental Gerontology, vol.39, issue.9, pp.1369-1378, 2004.
DOI : 10.1016/j.exger.2004.07.002

J. Chen, Z. Shi, and J. Dong, Evaluation of x-inactivation status and cytogenetic stability of human dermal fibroblasts after long-term culture, Int J Cell Biol, p.289653, 2010.

M. Allahbakhshian-farsani, N. Abdian, and P. Ghasemi-dehkordi, Cytogenetic analysis of human dermal fibroblasts (HDFs) in early and late passages using both karyotyping and comet assay techniques, Cytotechnology, 2013.

R. Shmueli, J. Sunshine, Z. Xu, E. Duh, and J. Green, Gene delivery nanoparticles specific for human microvasculature and macrovasculature, Nanomedicine: Nanotechnology, Biology and Medicine, vol.8, issue.7, pp.1200-1207, 2012.
DOI : 10.1016/j.nano.2012.01.006

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350835

S. Tzeng, P. Yang, W. Grayson, and J. Green, Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cells, Int J Nanomedicine, vol.6, pp.3309-3322, 2011.

S. Tzeng, B. Hung, W. Grayson, and J. Green, Cystamine-terminated poly(beta-amino ester)s for siRNA delivery to human mesenchymal stem cells and enhancement of osteogenic differentiation, Biomaterials, vol.33, issue.32, pp.8142-8151, 2012.
DOI : 10.1016/j.biomaterials.2012.07.036