Cyclodextrin Cavity-Induced Mechanistic Switch in Copper-Catalyzed Hydroboration
Résumé
N-heterocyclic carbene-capped cyclodextrin (ICyD) ligands, α-ICyD and β-ICyD derived from α- and β-cyclodextrin, respectively give opposite regioselectivities in a copper-catalyzed hydroboration. The site-selectivity results from two different mechanisms: the conventional parallel one and a new orthogonal mechanism. The shape of the cavity was shown not only to induce a regioselectivity switch but also a mechanistic switch. The scope of interest of the encapsulation of a reactive center is therefore broadened by this study.
Domaines
Chimie
Fichier principal
Mechanistic switch accepté non mis en page.pdf (612.72 Ko)
Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...