Hepatocellular Carcinoma, New England Journal of Medicine, vol.365, issue.12, pp.1118-1127, 2011. ,
DOI : 10.1056/NEJMra1001683
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets, Nature Genetics, vol.30, issue.5, pp.505-511, 2015. ,
DOI : 10.1371/journal.pone.0038686
URL : https://hal.archives-ouvertes.fr/inserm-01159736
Gene-expression Analysis Identifies Specific Patterns of Dysregulated Molecular Pathways and Genetic Subgroups of Human Hepatocellular Carcinoma, Anticancer Research, vol.36, issue.10, pp.5087-5095, 2016. ,
DOI : 10.21873/anticanres.11078
Exploration of liver cancer genomes, Nature Reviews Gastroenterology & Hepatology, vol.500, issue.6, pp.340-349, 2014. ,
DOI : 10.1038/nature12477
Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesis, Hepatology, vol.341, issue.1, pp.90-97, 1998. ,
DOI : 10.1002/hep.510280114
Replication error frequencies in primary hepatocellular carcinoma: a comparison of solitary primary versus multiple primary cancers, Liver, vol.13, issue.4, pp.272-276, 1998. ,
DOI : 10.1002/(SICI)1097-0142(19960415)77:8+<1620::AID-CNCR6>3.0.CO;2-H
Microsatellite instability in European hepatocellular carcinoma, Oncogene, vol.18, issue.1, pp.181-187, 1999. ,
DOI : 10.1038/sj.onc.1202279
Quantitative evaluation of genomic instability as a possible predictor for development of hepatocellular carcinoma: Comparison of loss of heterozygosity and replication error, Hepatology, vol.350, issue.6, pp.1246-1250, 2000. ,
DOI : 10.1053/jhep.2000.7298
Genetic Instability and Aberrant DNA Methylation in Chronic Hepatitis and Cirrhosis???A Comprehensive Study of Loss of Heterozygosity and Microsatellite Instability at 39 Loci and DNA Hypermethylation on 8 CpG Islands in Microdissected Specimens From Patients With Hepatocellular Carcinoma, Hepatology, vol.73, issue.5, pp.970-979, 2000. ,
DOI : 10.1053/jhep.2000.19797
Molecular Changes in Hepatocellular Dysplastic Nodules on Microdissected Liver Biopsies, Hepatology, vol.18, issue.5, pp.942-946, 2000. ,
DOI : 10.1053/jhep.2000.18425
Infrequent widespread microsatellite instability in hepatocellular carcinomas., International Journal of Oncology, vol.16, pp.543-547, 2000. ,
DOI : 10.3892/ijo.16.3.543
Genomic instability in chronic viral hepatitis and hepatocellular carcinoma, Human Pathology, vol.32, issue.7, pp.698-703, 2001. ,
DOI : 10.1053/hupa.2001.25593
and hMSH2 expression in human hepatocellular carcinoma Microsatellite alterations in human hepatocellular carcinoma infected with hepatitis B virus: Associated with the elevation of serum alphafetoprotein, Int J Oncol Int J Oncol, vol.19, issue.19, pp.1-567, 2001. ,
Allelic alterations in nontumorous liver tissues and corresponding hepatocellular carcinomas from chinese patients, Human Pathology, vol.34, issue.7, pp.699-705, 2003. ,
DOI : 10.1016/S0046-8177(03)00175-8
Microsatellite instability mutator phenotype in hepatocellular carcinoma in non-alcoholic and non-virally infected normal livers Clinicopathological significance of loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in China, Carcinogenesis World J Gastroenterol, vol.25, issue.11, pp.541-547, 2004. ,
Microsatellite instability in hepatocellular carcinoma in non-cirrhotic liver in patients older than 60???years, Hepatology Research, vol.61, issue.3, pp.266-273, 2009. ,
DOI : 10.3748/wjg.v5.i6.470
DNA mismatch repair defects: role in colorectal carcinogenesis, Biochimie, vol.84, issue.1, pp.27-47, 2002. ,
DOI : 10.1016/S0300-9084(01)01362-1
Review: Clinical aspects of hereditary DNA Mismatch repair gene mutations, DNA Repair, vol.38, pp.155-162, 2016. ,
DOI : 10.1016/j.dnarep.2015.11.018
Frequency of Deletions of EPCAM (TACSTD1) in MSH2-Associated Lynch Syndrome Cases, The Journal of Molecular Diagnostics, vol.13, issue.1, pp.93-99, 2011. ,
DOI : 10.1016/j.jmoldx.2010.11.011
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines, Cancer Res, vol.57, pp.808-811, 1997. ,
The mutator pathway is a feature of immunodeficiency-related lymphomas, Proceedings of the National Academy of Sciences, vol.116, issue.6, pp.5002-5007, 2004. ,
DOI : 10.1016/S0016-5085(99)70499-3
URL : https://hal.archives-ouvertes.fr/hal-00023370
Oxidative stress increases frameshift mutations in human colorectal cancer cells, Cancer Res, vol.61, pp.7444-7448, 2001. ,
Oxidative stress inactivates the human DNA mismatch repair system, AJP: Cell Physiology, vol.283, issue.1, pp.148-154, 1995. ,
DOI : 10.1152/ajpcell.00422.2001
Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis Upregulation of microRNA-155 promotes cancer cell invasion and CANCER (2017) predicts poor survival of hepatocellular carcinoma following liver transplantation, promotes migration and invasion by the miR-21-PDCD4-AP- 1 feedback loop in human hepatocellular carcinoma, pp.1237-1240, 1996. ,
Overexpression of microRNAs-155 and 21 targeting mismatch repair proteins in inflammatory bowel diseases, Carcinogenesis, vol.34, issue.4, pp.828-834, 2013. ,
DOI : 10.1093/carcin/bgs408
Modulation of mismatch repair and genomic stability by miR-155, Proceedings of the National Academy of Sciences, vol.69, issue.17, pp.6982-6987, 2010. ,
DOI : 10.1158/0008-5472.CAN-09-0358
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2), Proceedings of the National Academy of Sciences, vol.6, issue.4, pp.21098-21103, 1964. ,
DOI : 10.1016/j.ijrobp.2007.02.018
A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors 38 Soreide K: High-fidelity of five quasimonomorphic mononucleotide repeats to high-frequency microsatellite instability distribution in early-stage adenocarcinoma of the colon, M, May E and Debuire B: Frequent microsatellite instability in post hepatitis B viral cirrhosis, pp.5248-5257, 1996. ,
Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR, Gastroenterology, vol.123, issue.6, pp.1804-1811, 2002. ,
DOI : 10.1053/gast.2002.37070
Experimental limits of PCR analysis of (CA)n repeat alterations, Trends in Genetics, vol.12, issue.11, pp.450-452, 1996. ,
DOI : 10.1016/0168-9525(96)99996-5
The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells, Cancer Res, vol.61, pp.6555-6562, 2001. ,
Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer, Cancer Res, vol.63, pp.5738-5744, 2003. ,
Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract, Oncogene, vol.22, issue.14, pp.2113-2118, 2006. ,
DOI : 10.1155/2004/159347
Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability, Oncogene, vol.1, issue.40, pp.5919-5926, 2007. ,
DOI : 10.1038/sj.onc.1210419
Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treated by 5-fluorouracil and leucovorin with or without oxaliplatin, Annals of Oncology, vol.21, issue.4, pp.772-780, 2010. ,
DOI : 10.1093/annonc/mdp383
Defective Mismatch Repair Status as a Prognostic Biomarker of Disease-Free Survival in Stage III Colon Cancer Patients Treated with Adjuvant FOLFOX Chemotherapy, Clinical Cancer Research, vol.17, issue.23, pp.7470-7478, 2011. ,
DOI : 10.1158/1078-0432.CCR-11-1048
Oxidative stress-mediated biomolecular damage and inflammation in tumorigenesis, In Vivo, vol.26, pp.395-402, 2012. ,
The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutS??, Cell, vol.153, issue.3, pp.590-600, 2013. ,
DOI : 10.1016/j.cell.2013.03.025
The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production, Virology, vol.462, issue.463, pp.462-463, 2014. ,
DOI : 10.1016/j.virol.2014.05.016