Genetics of Early Onset Cognitive Impairment, Annual Review of Genomics and Human Genetics, vol.11, issue.1, pp.161-187, 2010. ,
DOI : 10.1146/annurev-genom-082509-141640
Genetic and Epigenetic Networks in Intellectual Disabilities, Annual Review of Genetics, vol.45, issue.1, pp.81-104, 2011. ,
DOI : 10.1146/annurev-genet-110410-132512
Rho-linked genes and neurological disorders, Pfl??gers Archiv - European Journal of Physiology, vol.44, issue.5, pp.787-797, 2008. ,
DOI : 10.1007/s00424-007-0385-1
Oncogenes on my mind: ERK and MTOR signaling in cognitive diseases, Trends in Genetics, vol.24, issue.10, pp.498-510, 2008. ,
DOI : 10.1016/j.tig.2008.07.005
Deep sequencing reveals 50 novel genes for recessive cognitive disorders, Nature, vol.43, issue.7367, pp.57-63, 2011. ,
DOI : 10.1038/ng.826
Emerging major synaptic signaling pathways involved in intellectual disability, Molecular Psychiatry, vol.104, issue.7, pp.682-693, 2012. ,
DOI : 10.1073/pnas.0610059104
Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses, Neuron, vol.70, issue.5, pp.898-907, 2011. ,
DOI : 10.1016/j.neuron.2011.05.021
Reversing Neurodevelopmental Disorders in Adults, Neuron, vol.60, issue.6, pp.950-960, 2008. ,
DOI : 10.1016/j.neuron.2008.12.007
URL : http://doi.org/10.1016/j.neuron.2008.12.007
100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future, Nature Reviews Neuroscience, vol.63, issue.7, pp.514-522, 2010. ,
DOI : 10.1113/jphysiol.1976.sp011592
Drosophila modeling of heritable neurodevelopmental disorders, Current Opinion in Neurobiology, vol.21, issue.6, pp.834-841, 2011. ,
DOI : 10.1016/j.conb.2011.04.009
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172335
Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome, Annual Review of Medicine, vol.62, issue.1, pp.411-429, 2011. ,
DOI : 10.1146/annurev-med-061109-134644
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila, Nature, vol.39, issue.7150, pp.151-156, 2007. ,
DOI : 10.1038/nature05954
Research resources for Drosophila: the expanding universe, Nature Reviews Genetics, vol.15, issue.3, pp.179-193, 2005. ,
DOI : 10.1016/0896-6273(95)90059-4
Systematic genetic analysis of muscle morphogenesis and function in Drosophila, Nature, vol.297, issue.7286, pp.287-291, 2010. ,
DOI : 10.1091/mbc.9.12.3505
Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi, Cell Stem Cell, vol.8, pp.580-593, 2011. ,
BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION, Proceedings of the National Academy of Sciences, vol.58, issue.3, pp.1112-1119, 1967. ,
DOI : 10.1073/pnas.58.3.1112
URL : http://doi.org/10.1073/pnas.58.3.1112
The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches, Human Molecular Genetics, vol.18, issue.3, pp.454-462, 2009. ,
DOI : 10.1093/hmg/ddn373
Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless, Development, vol.129, pp.3393-3402, 2002. ,
Reiterative Use of the EGF Receptor Triggers Differentiation of All Cell Types in the Drosophila Eye, Cell, vol.87, issue.4, pp.651-660, 1996. ,
DOI : 10.1016/S0092-8674(00)81385-9
A broad expression profile of the GMR-GAL4 driver in Drosophila melanogaster, Genetics and Molecular Research, vol.11, issue.3, pp.1997-2002 ,
DOI : 10.4238/2012.August.6.4
The v-ATPase V0 Subunit a1 Is Required for a Late Step in Synaptic Vesicle Exocytosis in Drosophila, Cell, vol.121, issue.4, pp.607-620, 2005. ,
DOI : 10.1016/j.cell.2005.03.012
to Study Phototransduction?, Journal of Neurogenetics, vol.40, issue.2, pp.55-66, 2010. ,
DOI : 10.1016/0092-8674(85)90344-7
CYFIP dependent Actin Remodeling controls specific aspects of Drosophila eye morphogenesis, Developmental Biology, vol.359, issue.1, pp.37-46, 2011. ,
DOI : 10.1016/j.ydbio.2011.08.009
CYFIP/Sra-1 Controls Neuronal Connectivity in Drosophila and Links the Rac1 GTPase Pathway to the Fragile X Protein, Sra-1 Controls Neuronal Connectivity in Drosophila and Links the Rac1 GTPase Pathway to the Fragile X Protein, pp.887-898, 2003. ,
DOI : 10.1016/S0896-6273(03)00354-4
Characterization of the proteome, diseases and evolution of the human postsynaptic density, Nature Neuroscience, vol.14, issue.1, pp.19-21, 2011. ,
DOI : 10.1371/journal.pone.0003964
Measuring the physical cohesiveness of proteins using physical interaction enrichment, Bioinformatics, vol.26, issue.21, pp.2737-2743, 2010. ,
DOI : 10.1093/bioinformatics/btq474
Tumor suppressors and cell metabolism: a recipe for cancer growth, Genes & Development, vol.23, issue.5, pp.537-548, 2009. ,
DOI : 10.1101/gad.1756509
URL : http://genesdev.cshlp.org/content/23/5/537.full.pdf
Ribosomal S6 Kinase 2 Is a Key Regulator in Tumor Promoter Induced Cell Transformation, Cancer Research, vol.67, issue.17, pp.8104-8112, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-4668
Upregulation of myosin Va by Snail is involved in cancer cell migration and metastasis, International Journal of Cancer, vol.28, issue.1, pp.53-64, 2010. ,
DOI : 10.1016/0092-8674(93)90675-G
Myosin Va Mutation in Rats Is an Animal Model for the Human Hereditary Neurological Disease, Griscelli Syndrome Type 1, Annals of the New York Academy of Sciences, vol.1086, issue.1, 2006. ,
DOI : 10.1196/annals.1377.006
The Roles of the Dystrophin-Associated Glycoprotein Complex at the Synapse, Molecular Neurobiology, vol.103, issue.8, pp.1-21, 2010. ,
DOI : 10.1113/jphysiol.1973.sp010273
DNA Damage, Somatic Aneuploidy, and Malignant Sarcoma Susceptibility in Muscular Dystrophies, PLoS Genetics, vol.6, issue.4, p.1002042, 2011. ,
DOI : 10.1371/journal.pgen.1002042.s001
URL : http://doi.org/10.1371/journal.pgen.1002042
A signaling role for dystrophin: Inhibiting skeletal muscle atrophy pathways, Cancer Cell, vol.8, issue.5, pp.351-352, 2005. ,
DOI : 10.1016/j.ccr.2005.10.016
URL : http://doi.org/10.1016/j.ccr.2005.10.016
Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability, Molecular Psychiatry, vol.19, issue.11, pp.1103-1118, 2011. ,
DOI : 10.1038/ng2109
Overexpression of Glycosylphosphatidylinositol (GPI) Transamidase Subunits Phosphatidylinositol Glycan Class T and/or GPI Anchor Attachment 1 Induces Tumorigenesis and Contributes to Invasion in Human Breast Cancer, Cancer Research, vol.66, issue.20, pp.9829-9836, 2006. ,
DOI : 10.1158/0008-5472.CAN-06-0506
The Human Phenotype Ontology: A Tool for Annotating and Analyzing Human Hereditary Disease, The American Journal of Human Genetics, vol.83, issue.5, pp.610-615, 2008. ,
DOI : 10.1016/j.ajhg.2008.09.017
The Biological Coherence of Human Phenome Databases, The American Journal of Human Genetics, vol.85, issue.6, pp.801-808, 2009. ,
DOI : 10.1016/j.ajhg.2009.10.026
Phenome connections, Trends in Genetics, vol.24, issue.3, pp.103-106, 2008. ,
DOI : 10.1016/j.tig.2007.12.005
CEP89 is required for mitochondrial metabolism and neuronal function in man and fly, Human Molecular Genetics, vol.22, issue.15, pp.3138-3151, 2013. ,
DOI : 10.1093/hmg/ddt170
CDK19 is disrupted in a female patient with bilateral congenital retinal folds, microcephaly and mild mental retardation, Human Genetics, vol.42, issue.3, pp.281-291, 2010. ,
DOI : 10.1016/0002-9394(82)90316-6
SLC29A3 gene is mutated in pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway, Human Molecular Genetics, vol.18, issue.12, pp.2257-2265, 2009. ,
DOI : 10.1093/hmg/ddp161
Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi, Nature, vol.314, issue.7241, pp.987-992, 2009. ,
DOI : 10.1016/j.cub.2004.01.023
A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1, Genes & Development, vol.26, issue.13, pp.1421-1426, 2012. ,
DOI : 10.1101/gad.190876.112
Genetics and molecular basis of human peroxisome biogenesis disorders, BBA) - Molecular Basis of Disease 1822, pp.1430-1441, 2012. ,
DOI : 10.1016/j.bbadis.2012.04.006
Oligosaccharyltransferase-Subunit Mutations in Nonsyndromic Mental Retardation, The American Journal of Human Genetics, vol.82, issue.5, pp.1150-1157, 2008. ,
DOI : 10.1016/j.ajhg.2008.03.021
URL : http://doi.org/10.1016/j.ajhg.2008.03.021
Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development, Proceedings of the National Academy of Sciences, vol.15, issue.3, pp.15750-15755, 2009. ,
DOI : 10.1023/A:1016078832697
URL : http://www.pnas.org/content/106/37/15750.full.pdf
Phenomics: the next challenge, Nature Reviews Genetics, vol.11, issue.113, pp.855-866, 2010. ,
DOI : 10.1038/ng1007-1181
Phenomics: the systematic study of phenotypes on a genome-wide scale, Neuroscience, vol.164, issue.1, pp.30-42, 2009. ,
DOI : 10.1016/j.neuroscience.2009.01.027
Fruit flies and intellectual disability, Fly, vol.3, issue.1, pp.91-104, 2009. ,
DOI : 10.4161/fly.3.1.7812
URL : http://www.tandfonline.com/doi/pdf/10.4161/fly.3.1.7812?needAccess=true
Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities, Cold Spring Harbor Perspectives in Biology, vol.4, issue.3, p.9886, 2012. ,
DOI : 10.1101/cshperspect.a009886
URL : http://cshperspectives.cshlp.org/content/4/3/a009886.full.pdf
Systematic discovery of nonobvious human disease models through orthologous phenotypes, Proceedings of the National Academy of Sciences, vol.415, issue.6873, pp.6544-6549, 2010. ,
DOI : 10.1038/415757a
Cohesin controls planar cell polarity by regulating the level of the seven-pass transmembrane cadherin Flamingo, Genes to Cells, vol.320, issue.6, pp.509-524, 2012. ,
DOI : 10.1126/science.1155244
Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity, Developmental Cell, vol.21, issue.1, pp.120-133, 2011. ,
DOI : 10.1016/j.devcel.2011.06.011
URL : http://doi.org/10.1016/j.devcel.2011.06.011
Arl13b in Primary Cilia Regulates the Migration and Placement of Interneurons in the Developing Cerebral Cortex, Developmental Cell, vol.23, issue.5, pp.925-938, 2012. ,
DOI : 10.1016/j.devcel.2012.09.019
An Efficient Genetic Screen in Drosophila to Identify Nuclear-Encoded Genes With Mitochondrial Function, Genetics, vol.174, issue.1, pp.525-533, 2006. ,
DOI : 10.1534/genetics.106.061705
The Structural and Functional Role of Med5 in the Yeast Mediator Tail Module, Journal of Biological Chemistry, vol.159, issue.50, pp.41366-41372, 2005. ,
DOI : 10.1093/emboj/18.3.522
Identification of functional elements and regulatory circuits by Drosophila modENCODE, Science, vol.330, pp.1787-1797, 2010. ,
The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals, Science, vol.38, issue.7, pp.1091-1097, 2011. ,
DOI : 10.1130/G30726.1
Adult reversal of cognitive phenotypes in neurodevelopmental disorders, Journal of Neurodevelopmental Disorders, vol.320, issue.2, pp.150-157, 2009. ,
DOI : 10.1126/science.1150516
Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a, PLoS Biology, vol.46, issue.1, p.1000569, 2011. ,
DOI : 10.1371/journal.pbio.1000569.s012
Identification of human haploinsufficient genes and their genomic proximity to segmental duplications, European Journal of Human Genetics, vol.79, issue.11, pp.1350-1357, 2008. ,
DOI : 10.1038/ejhg.2008.111
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes, Development, vol.118, pp.401-415, 1993. ,
GAL4 causes developmental defects and apoptosis when expressed in the developing eye of Drosophila melanogaster, Genet Mol Res, vol.2, pp.43-47, 2003. ,
Synaptojanin Is Recruited by Endophilin to Promote Synaptic Vesicle Uncoating, Neuron, vol.40, issue.4, pp.733-748, 2003. ,
DOI : 10.1016/S0896-6273(03)00644-5
URL : http://doi.org/10.1016/s0896-6273(03)00644-5
FlyBase: enhancing Drosophila Gene Ontology annotations, Nucleic Acids Research, vol.37, issue.Database, pp.555-559, 2009. ,
DOI : 10.1093/nar/gkn788
URL : https://academic.oup.com/nar/article-pdf/37/suppl_1/D555/3289397/gkn788.pdf
ESTablishing a human transcript map, Nature Genetics, vol.22, issue.4, pp.369-371, 1995. ,
DOI : 10.1038/368032a0
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nature Protocols, vol.99, issue.1, pp.44-57, 2008. ,
DOI : 10.6026/97320630002428
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists, Nucleic Acids Research, vol.37, issue.1, pp.1-13, 2009. ,
DOI : 10.1093/nar/gkn923
Human Protein Reference Database--2009 update, Nucleic Acids Research, vol.37, issue.Database, pp.767-772, 2009. ,
DOI : 10.1093/nar/gkn892
Building and analyzing protein interactome networks by cross-species comparisons, BMC Systems Biology, vol.4, issue.1, p.36, 2010. ,
DOI : 10.1186/1752-0509-4-36
URL : https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/1752-0509-4-36?site=bmcsystbiol.biomedcentral.com
A Protein Complex Network of Drosophila melanogaster, Cell, vol.147, issue.3, pp.690-703, 2011. ,
DOI : 10.1016/j.cell.2011.08.047
DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila, Nucleic Acids Research, vol.39, issue.suppl_1, pp.736-743, 2010. ,
DOI : 10.1093/nar/gkq1092
URL : https://academic.oup.com/nar/article-pdf/39/suppl_1/D736/18785736/gkq1092.pdf
DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions, BMC Genomics, vol.9, issue.1, p.461, 2008. ,
DOI : 10.1186/1471-2164-9-461
Circos: An information aesthetic for comparative genomics, Genome Research, vol.19, issue.9, pp.1639-1645, 2009. ,
DOI : 10.1101/gr.092759.109
URL : http://genome.cshlp.org/content/19/9/1639.full.pdf
Cytoscape 2.8: new features for data integration and network visualization, Bioinformatics, vol.27, issue.3, pp.431-432, 2011. ,
DOI : 10.1093/bioinformatics/btq675
ExprEssence - Revealing the essence of differential experimental data in the context of an interaction/regulation net-work, BMC Systems Biology, vol.4, issue.1, p.164, 2010. ,
DOI : 10.1186/1752-0509-4-164
A text-mining analysis of the human phenome, European Journal of Human Genetics, vol.68, issue.5, pp.535-542, 2006. ,
DOI : 10.1038/sj.ejhg.5201585
Kismet/CHD7 regulates axon morphology, memory and locomotion in a Drosophila model of CHARGE syndrome, Human Molecular Genetics, vol.19, issue.21, pp.4253-4264, 2010. ,
DOI : 10.1093/hmg/ddq348
Trio Combines with Dock to Regulate Pak Activity during Photoreceptor Axon Pathfinding in Drosophila, Cell, vol.101, issue.3, pp.283-294, 2000. ,
DOI : 10.1016/S0092-8674(00)80838-7
Semaphorin3A regulates axon growth independently of growth cone repulsion via modulation of TrkA signaling, Cellular Signalling, vol.20, issue.3, pp.467-479, 2008. ,
DOI : 10.1016/j.cellsig.2007.10.023
cul-1 Is Required for Cell Cycle Exit in C. elegans and Identifies a Novel Gene Family, Cell, vol.85, issue.6, pp.829-839, 1996. ,
DOI : 10.1016/S0092-8674(00)81267-2
A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice, Developmental Biology, vol.340, issue.1, pp.41-53, 2010. ,
DOI : 10.1016/j.ydbio.2010.01.017
Tubulin-related cortical dysgeneses: microtubule dysfunction underlying neuronal migration defects, Trends in Genetics, vol.25, issue.12, pp.555-566, 2009. ,
DOI : 10.1016/j.tig.2009.10.003
??PIX Associates with Calpain 4, the Small Subunit of Calpain, and Has a Dual Role in Integrin-mediated Cell Spreading, Journal of Biological Chemistry, vol.23, issue.8, pp.6879-6889, 2005. ,
DOI : 10.1074/jbc.M105198200
Different effects of TrkA expression in neuroblastoma cell lines with or withoutMYCN amplification, Medical and Pediatric Oncology, vol.12, issue.6, pp.623-627, 2000. ,
DOI : 10.1038/313404a0
A SP1/MIZ1/MYCN Repression Complex Recruits HDAC1 at the TRKA and p75NTR Promoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF, Cancer Research, vol.71, issue.2, pp.404-412, 2011. ,
DOI : 10.1158/0008-5472.CAN-10-2627
A signaling role for dystrophin: Inhibiting skeletal muscle atrophy pathways, Cancer Cell, vol.8, issue.5, pp.351-352, 2005. ,
DOI : 10.1016/j.ccr.2005.10.016
URL : http://doi.org/10.1016/j.ccr.2005.10.016
Cohesin controls planar cell polarity by regulating the level of the seven-pass transmembrane cadherin Flamingo, Genes to Cells, vol.320, issue.6, pp.509-524, 2012. ,
DOI : 10.1126/science.1155244
Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity, Developmental Cell, vol.21, pp.120-133, 2011. ,
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition, Nature Genetics, vol.43, issue.8, pp.776-784, 2011. ,
DOI : 10.1038/ng.662
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145011
CC2D2A Is Mutated in Joubert Syndrome and Interacts with the Ciliopathy-Associated Basal Body Protein CEP290, The American Journal of Human Genetics, vol.83, issue.5, pp.559-571, 2008. ,
DOI : 10.1016/j.ajhg.2008.10.002
In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse, Human Molecular Genetics, vol.15, issue.11, pp.1847-1857, 2006. ,
DOI : 10.1093/hmg/ddl107
Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE, Science, vol.330, pp.1787-1797, 2010. ,