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A. We, T. T. Li, G. Tribello, and S. J. , Cox for comments and suggestions. This work was supported by the European Research Council under the European Union's Seventh Framework Programme (FPERC Grant Agreement No. 616121 (HeteroIce project). A.M. is supported by the Royal Society through a Royal Society Wolfson Research Merit Award. We are grateful for computational resources provided by the London Center for Nanotechnology, the UCL Grace High Performance Computing Facility (Grace@UCL), the Materials Chemistry Consortium through the EPSRC Grant No. EP/L000202 and the UK Materials and Molecular Modeling Hub for computational resources, which is partially funded by EPSRC, This work was supported by French state funds managed by the ANR within the Investissements d'Avenir programme under reference ANR-11-IDEX-0004-02, within the framework of the cluster of excellence MATériaux Interfaces Surfaces Environnement (MATISSE) led by Sorbonne Universités, 2007.

M. F. Author, G. C. , and A. M. , conceived the research. M.F. performed the simulations and analysis. F.P. and S.P. contributed to the metadynamics simulations and analysis